If they are ever playing in your area and you love great live music, you simply must see Zappa Plays Zappa.
Just saw them Monday night here in Atlanta and they absolutely killed live. Very rare to see that level of musical skill displayed by younger musicians in this day and age. Frank would be (probably is somewhere) proud of Dweezil's brilliantly successful attempt to expose the music of his father, perhaps one of the greatest 20th century composers America has ever produced, Frank Zappa.
If you like rock, jazz, classical, avant-garde, funk or whatever type of music, you would do well to check them out.
They have some video up at their site:
http://www.zappaplayszappa.com/