Mojo - Both speakers are toed in, and in an AB ... AB arrangement. When reading my post, keep in mind it was the Legacy's that sounded more like the studio, not the Axioms.
I am fairly certain plugging ports on the M100's will "flesh out" vocals more. There is some emphasis in the 40 Hz range on the Axioms with all the ports open. This happens to be a sound I like, but it may also be causing (female) vocals to be a bit harder to define on the M100's than the Legacy's.
I did do more male vocal listening last night, and the M100's are actually a little clearer on male vocals. The differences in both male and female vocal clarity on both speakers is excellent - the best I have ever owned.