You are saying this based on experience?
I have heard a pair of M80ti's and I have owned a pair of M80.V4's and I would not say they were night and day different. I thought that both of them sounded exceptional and yes the .V4 did sound better but I could not put my finger on what was different.
I am basing my opinion on psychoacoustics in you brain will have a very hard time to distinguish two sounds that are very close to each other if you don't sample them back to back several times.
Perhaps it is just me as I am not a trained listener