Are you talking about mounting the M22s at ceiling height (not great), or just talking about using mounting brackets attached to the ceiling rather than the floor or wall ?
The speakers don't care whether the stand goes "down" or "up"
I always thought some nicely made brackets coming down 4-5 feet from the ceiling would look VERY sharp. You could mount the speakers at a decent listening height but never have to worry about knocking them over or even vacuuming around them. Wires could run through the ceiling and straight down to the speakers.
Hmm. I wonder what it would take to ceiling mount my M60s