Dave, I would not mount the M22s directly flat against the wall, I would use the brackets that axiom sells that allow you to angle them towards the listen position. I use them now for my bedroom, and I can't image the in-walls or on-walls sounding better than the bookshelves bracketed to the wall.
This is why I gave up on the in-wall or on-wall speakers. It's either mounted book shelves on large brackets that allow them to be angled in any direction or floor standing. The more I am reading however, I think I mine as well just go with the floor standing. Even though the top of the floor standing speakers would be about even with the bottom of the TV it should not ruin the sound stage. Maybe I should draw a rough diagram.