Quite possibly.... My room is 17x18x8 or thereabouts, and I've got M50s. They seem to fit pretty well in here. I could see the EP500 blowing you out of the water, but I could be wrong. The VP150 can be used with a number of center channel stands, and I think it has the ol' tripod mount type screw hole in the back. It's flat on the bottom.

I am the Doctor, and THIS... is my SPOON!